Elton Brand added 17 points and Andres Nocioni notched a double-double with 10 points and 10 rebounds for Philadelphia, which returned home after an eight- game road trip.
Thaddeus Young contributed 11 points in a reserve role for the Sixers, who topped Washington for the first time since winning four straight during the 2008-09 season.
"Needless to say, it is nice to beat Washington," Sixers coach Doug Collins said. "Our guys would not lose that game, and I was very proud of them for that."
Nick Young led the Wizards with 21 points. Rookie John Wall finished with 18 points and 14 assists and Rashard Lewis added a double-double with 18 points and 10 rebounds for Washington, which has yet to win a game on the road this season (0-17).
"We've got to make clutch plays in clutch situations as far as on the road," Wizards coach Flip Saunders said. "Our margin of error is not that much."
